Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition
Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition
Several studies have demonstrated that hematopoietic cells originate from endothelium in early development; however, the phenotypic progression of progenitor cells during human embryonic hemogenesis is not well described. Here, we define the developmental hierarchy among intermediate populations of hematopoietic progenitor cells (HPCs) derived from human embryonic stem cells (hESCs).
Genetic variation in metabolic phenotypes: study designs and applications
Many complex disorders are linked to metabolic phenotypes. Revealing genetic influences on metabolic phenotypes is key to a systems-wide understanding of their interactions with environmental and lifestyle factors in their aetiology, and we can now explore the genetics of large panels of metabolic traits by coupling genome-wide association studies and metabolomics.
Efficient Direct Reprogramming of Mature Amniotic Cells into Endothelial Cells by ETS Factors and TGF beta Suppression
Efficient Direct Reprogramming of Mature Amniotic Cells into Endothelial Cells by ETS Factors and TGF beta Suppression
ETS transcription factors ETV2, FLI1, and ERG1 specify pluripotent stem cells into induced vascular endothelial cells (iVECs). However, iVECs are unstable and drift toward nonvascular cells. We show that human midgestation c-Kit− lineage-committed amniotic cells (ACs) can be reprogrammed into vascular endothelial cells (rAC-VECs) without transitioning through a pluripotent state.
iTRAQ-Based Quantitative Protein Expression Profiling and MRM Verification of Markers in Type 2 Diabetes
The pathogenesis of Type 2 diabetes mellitus (T2DM) is complex owing to molecular heterogeneity in the afflicted population. Current diagnostic methods rely on blood glucose measurements, which are noninformative with respect to progression of the disease to other associated pathologies. Thus, predicting the risk and development of T2DM-related complications, such as cardiovascular disease, remains a major challenge.
Speed Sensorless Induction Motor Drive With Predictive Current Controller
Speed Sensorless Induction Motor Drive With Predictive Current Controller
Today, speed sensorless modes of operation are becoming standard solutions in the area of electric drives. This paper presents a speed sensorless control system of an induction motor with a predictive current controller.
Quantum resources for hybrid communication via qubit-oscillator states
Quantum resources for hybrid communication via qubit-oscillator states
We investigate a family of qubit-oscillator states as resources for hybrid quantum communication. They result from a mechanism of qubit-controlled displacement on the oscillator. For large displacements, we obtain analytical formulas for entanglement and other nonclassical correlations, such as entropic and geometric discord, in those states.
Intervention in biological phenomena modeled by S-systems
Intervention in biological phenomena modeled by S-systems
Recent years have witnessed extensive research activity in modeling biological phenomena as well as in developing intervention strategies for such phenomena. S-systems, which offer a good compromise between accuracy and mathematical flexibility, are a promising framework for modeling the dynamical behavior of biological phenomena. In this paper, two different intervention strategies, namely direct and indirect, are proposed for the S-system model.
Inverse spectral problems for differential operators on arbitrary compact graphs
Inverse spectral problems for differential operators on arbitrary compact graphs
Inverse problems of spectral analysis are studied for Sturm-Liouville differential operators on arbitrary compact graphs.
Enhanced compressive response of hybrid Mg-CNT nano-composites
Enhanced compressive response of hybrid Mg-CNT nano-composites
Uniaxial compressive properties of hybrid Mg/Al–CNT nano-composites are studied in the present paper. Hybrid nano-composites were fabricated using powder metallurgy route followed by microwave assisted rapid sintering technique and hot extrusion.
Subwavelength optical microscopy in the far field
Subwavelength optical microscopy in the far field
We present a procedure for subwavelength optical microscopy. The identical atoms are distributed on a plane and shined with a standing wave.
On the Diversity Enhancement and Power Balancing of Per-Subcarrier Transmit Antenna Selection in OFDM Systems
On the Diversity Enhancement and Power Balancing of Per-Subcarrier Transmit Antenna Selection in OFDM Systems
In this paper, we consider multicarrier systems with multiple transmit antennas under a power-balancing constraint.
Exact spatiotemporal wave and soliton solutions to the generalized (3+1)-dimensional nonlinear Schrodinger equation with linear potential
Exact spatiotemporal wave and soliton solutions to the generalized (3+1)-dimensional nonlinear Schrodinger equation with linear potential
Exact extended traveling wave and spatiotemporal soliton solutions to the generalized (3+1)-dimensional Schrödinger equation with distributed coefficients and linear potential are found.
Joint rate, power, and decoding order optimization of multiuser MIMO systems
Joint rate, power, and decoding order optimization of multiuser MIMO systems
We consider multiuser MIMO systems with some of the users having target-rate requirements while the other users are working on best-effort data transmission. Both multiple-access channels (MAC) and broadcast channels (BC) are considered.
Joint Power and Resource Allocation for Block-Fading Relay-Assisted Broadcast Channels
Joint Power and Resource Allocation for Block-Fading Relay-Assisted Broadcast Channels
We provide the solution for optimizing the power and resource allocation over block-fading relay-assisted broadcast channels in order to maximize the long term average achievable rates region of the users.
Gaussian-state entanglement in a quantum beat laser
Gaussian-state entanglement in a quantum beat laser
Recently quantum beat lasers have been considered as a source of entangled radiation [ S. Qamar, F. Ghafoor, M. Hillery and M. S. Zubairy Phys. Rev. A 77062308 (2008)].